Speaker
Alun Lloyd
(North Carolina State University)
Description
Gene drives are a powerful technique to reduce the size of a population or to transform it to become less troublesome. Major concerns include accidental escape of a gene drive, which might lead to widespread elimination of a species, or unintended consequences of released individuals, which might include evolution of resistance to an effector gene. Both spatial localization of a gene drive and the ability to reverse a gene drive are desirable mechanisms to increase the safety of drives. A number of such approaches have been proposed in the literature. Using mathematical modelling, we will explore their likely efficacy and discuss critical weaknesses.
Primary author
Alun Lloyd
(North Carolina State University)
Co-authors
Ms
Jaye Sudweeks
(North Carolina State University)
Mr
Michael Vella
(North Carolina State University)
Dr
Sumit Dhole
(North Carolina State University)
Dr
Fred Gould
(North Carolina State University)
