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SUMMARY:Modelling the spread of antimicrobial resistance in hospital
DTSTART;VALUE=DATE-TIME:20180711T064000Z
DTEND;VALUE=DATE-TIME:20180711T070000Z
DTSTAMP;VALUE=DATE-TIME:20210228T010418Z
UID:indico-contribution-310@conferences.maths.unsw.edu.au
DESCRIPTION:Speakers: Mochamad Apri (Dept. of Mathematics\, Institut Tekno
 logi Bandung\, Indonesia)\nAntibiotic resistance has become one of the maj
 or health issues in the world. It kills around 700\,000 people each year w
 orldwide\, and will become even worse if no new antibiotics are developed 
 (Nature\, 2017). Therefore\, serious efforts are required to prevent more 
 severe conditions in the future. One important effort in this case is unde
 rstanding the dynamics of the problem so that effective policies can be pr
 epared. To understand the dynamics of the problem\, we propose a mathemati
 cal model that describes the interaction between sensitive and resistant b
 acteria with human population. Here\, we focus on the spread of antimicrob
 ial resistance in the hospital environment. We assume that bacteria popula
 tion can be grouped into two compartments\; resistant and sensitive popula
 tions\, whereas patients population can be distinguished as uncolonized pa
 tient\, sensitive-colonized patient\, or resistant-colonized patient. Thus
 \, the model that we develop is a two-level population model. A sensitive 
 bacterium can be resistant due to\, e.g.\, interactions with resistant bac
 teria\, gene mutation\, etc. An uncolonized patient or sensitive-colonized
  patient can be contaminated by resistant bacteria when he/she gets contac
 t with unsterilized medical equipment\, contaminated environment\, etc. We
  consider the cases when patients are treated and not treated with antibio
 tics. In the first case\, even if we consider that all patients that are a
 dministered to the hospital are uncolonized\, eventually all of them will 
 become colonized by resistant bacteria from the environment after a certai
 n time interval. Therefore\, apart from applying different strategies on t
 he use of antibiotic\, hygiene of environment is also playing crucial role
  in controlling the spread of the resistance. We show this via stability o
 f the disease-free and endemic equilibrium of the model. Some numerical si
 mulations will also be presented.\n\nhttps://conferences.maths.unsw.edu.au
 /event/2/contributions/310/
LOCATION:University of Sydney New Law School/--028
URL:https://conferences.maths.unsw.edu.au/event/2/contributions/310/
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