BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//CERN//INDICO//EN
BEGIN:VEVENT
SUMMARY:Regression of tumour cells in breast cancer administrating chemoth
 erapy using MTD and metronomic techniques
DTSTART;VALUE=DATE-TIME:20180709T094500Z
DTEND;VALUE=DATE-TIME:20180709T100000Z
DTSTAMP;VALUE=DATE-TIME:20210228T010107Z
UID:indico-contribution-361@conferences.maths.unsw.edu.au
DESCRIPTION:Speakers: Fatemeh Ansarizadeh ()\nTo gain deep insights into t
 he interactions among major types of cells\, such as healthy\, tumour\, an
 d immune cells\, in a tumour-bearing host\, we propose a mathematical mode
 l consisting of four delay differential equations by considering the inher
 ent delay in the tumour cells’ life cycle. When choosing model parameter
 s\, sensitivity analysis justified previous assumptions had been considere
 d.\n\nSince the impact of immune system is decisive on the regression of t
 umour cells\, stability analysis is performed for two different levels of 
 immune system surveillance\, that is\, healthy and compromised tumour-bear
 ing host. \n\nTheoretically\, it has been showed that in a healthy host th
 e immune system is able to eradicate the tumour cells completely whereas i
 n presence of weak immune system tumour cells have the opportunity to keep
  proliferating.\n\nThe latter case\, necessitates an efficient treatment\,
  and more precisely a combination of different treatments\, for being able
  to fight and demise tumour cells.\n\nNowadays\, Chemotherapy is the most 
 common treatment which is administrated in various protocols. Among them\,
  MTD (Maximum Tolerated Dosage) and Metronomic are of great significance i
 n clinical observations. Our model suggests that Metronomic technique surp
 asses MTD after introducing this treatment. The last but not the least\, s
 ince the results of mathematical experiments illustrate the administrated 
 Chemotherapy protocols are not able to eradicate the tumour cells\, the pr
 oposed model unveils the demand for an adjunct treatment.\n\nhttps://confe
 rences.maths.unsw.edu.au/event/2/contributions/361/
LOCATION:University of Sydney Holme Building/--The Refectory
URL:https://conferences.maths.unsw.edu.au/event/2/contributions/361/
END:VEVENT
END:VCALENDAR