Visualising mitochondrial networks in a beating heart cell

11 Jul 2018, 15:30
New Law School/--107 (University of Sydney)

New Law School/--107

University of Sydney

Oral Presentation Minisymposium: Transport Phenomena in Biological Processes Transport phenomena in biological processes


Adarsh Kumbhari (University of Sydney)


Mitochondria are specialised organelles that produce adenosine triphosphate (ATP), a molecule used by cells as an energy source. Mitochondria form dynamic networks that constantly undergo fission and fusion in response to increased ATP demand. There is a lack of high-resolution data tracking the reorganisation mitochondrial networks in a beating heart cell. We use an agent-based model to simulate a mitochondrial network reorganising in beating heart cell. Our visualisation highlights how mitochondrial networks respond to a variety of stressors such as increased cellular respiration and localised hypoxia.

Primary author

Adarsh Kumbhari (University of Sydney)


Vijay Rajagopal (University of Melbourne) Peter Kim (University of Sydney)

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