Speaker
Adarsh Kumbhari
(University of Sydney)
Description
Mitochondria are specialised organelles that produce adenosine triphosphate (ATP), a molecule used by cells as an energy source. Mitochondria form dynamic networks that constantly undergo fission and fusion in response to increased ATP demand. There is a lack of high-resolution data tracking the reorganisation mitochondrial networks in a beating heart cell. We use an agent-based model to simulate a mitochondrial network reorganising in beating heart cell. Our visualisation highlights how mitochondrial networks respond to a variety of stressors such as increased cellular respiration and localised hypoxia.
Primary author
Adarsh Kumbhari
(University of Sydney)
Co-authors
Vijay Rajagopal
(University of Melbourne)
Peter Kim
(University of Sydney)
