Conveners
Recent perspectives on mathematical epidemiology: Part A
- Robert Smith? (The University of Ottawa)
Recent perspectives on mathematical epidemiology: Part B
- Robert Smith? (The University of Ottawa)
Description
This minisymposium will bring together researchers to examine up-to-the-minute disease problems that showcase the usefulness and applicability of mathematical modelling to a world far beyond the mathematical community. The audience is the mathematical biologist with an interest in infectious disease. This includes students and researchers, mathematicians interested in seeing applications and biologists who wish to see how mathematics can be used to solve real problems. The minisymposium is interdisciplinary in nature and includes those trained as mathematicians, epidemiologists and immunologists.
There is an urgent need for more understanding of the effects of surveillance on malaria control. Indoor residual spraying has had beneficial effects on global malaria reduction, but resistance to the insecticide poses a threat to eradication. We develop a model of impulsive differential equations to account for a resistant strain of mosquitoes that is entirely immune to the insecticide. The...
The number of HIV+ individuals who develop end stage renal disease (ESRD) and require life-long dialysis treatment has been continually rising in some regions around the world. A differential equation-based mathematical model was developed to assess the impact of antiretroviral therapy on the progression to disease and to project the future prevalence of HIV+ ESRD. The goals of this study are...
Clinical trials of the four-dose RTS,S/AS01 vaccine for P. falciparum malaria demonstrated a protective effect in young children and, beginning in 2018, the vaccine will be evaluated through a large-scale pilot implementation program in Ghana, Kenya and Malawi. Recent evidence from a phase 2a challenge study indicates that varying the timing and amount of the fourth dose could further...
Severe diseases arising as sequelae of superficial skin and throat infections with group A Streptococcus (GAS) are important causes of morbidity and mortality worldwide. The observed high level of heterogeneity in GAS prevalence across various temporal and spatial settings suggests potentially complex dynamics of population transmission. One of the most visible indicators of heterogeneity is...
Equine Infectious Anemia Virus (EIAV), a retrovirus that establishes a persistent lifelong infection in horses and ponies, and which can be transmitted by vectors (biting flies), is endemic in regions with warm climates. With the advent of global warming, research have shown that vector-borne diseases may be on the rise. This study seeks to understand how climate change will affect the EIAV...
